"Due Date," starring Robert Downey Jr, Zach Galifianakis and Jamie Foxx
Basic story: Downey is a dude trying to get from Atlanta to LA to see the birth of his child, gets kicked off the plane, and is forced to go with Galifianakis on a road trip. Hilarity is what happens next.
That's because this movie has got the stars of Iron Man and The Hangover, along with the director of The Hangover. This means that you should probably make the safe choice between this and the probably stupid "Megamind." Watch this movie if you want to keep your soul.